Injectable Growth Hormone Peptides Bodybuilding Melanotan-II CAS 121062-08-6

Injectable Growth Hormone Peptides Bodybuilding Melanotan-II CAS 121062-08-6

Melanotan and Melanotan II

Contrasts	Melanotan	Melanotan II
Molecular Formula	C78H111N21O19	C50H69N15O9
Molecular Weight	1646.85 Dalton	1024.18 Dalton
Molecular Structure
Background	Melanotan (MT) and Melanotan II (MT-II) are both analogs of the alpha-melanocyte stimulating hormone (α-MSH) which is produced within the pituitary gland. Along with other melanocortins, they are responsible for various internal human functions including skin and hair pigmentation, appetite, libido and physical sexual arousal. Whilst these effects have been observed in both sexes.
Melanotan Dosage	Start with a dose of 1mg daily for the first two or three days and, if level of side effects permit, look to increase dosage by 0.25mg every day over the next several days until you reach a daily dosage of 2-3mg. This level should be adequate for most users, though some may wish to increase yet further, perhaps as high as 5mg daily in order to achieve a very deep tan. A maintenance phase as described above is then used.
Melanotan II Dosage	Start with a dose of 0.25mg. If side effects (primarily nausea) are not proving troublesome, attempt to increase daily dosage by 0.25mg where possible, until you reach 1-1.5mg daily. Most have found that this level will yield a very pleasing result and I can't see much point in increasing too much further unless a very deep tan was desired. As with Melanotan, once the desired level of tanning is reached, a maintenance phase is used.

What is Melanotan II?

Melanotan II is a cyclic lactam analog of the melanocortin alpha-Melanocyte Stimulating Hormone (α-MSH), a multifunctional peptide that regulates a broad array of physiological functions[1], including the stimulation of melanogenesis and aphrodisiac effects via melanocyte receptor activation. Melanotan II has not been approved for human use outside of clinical trials; however, it has been studied extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis stimulating properties. Resultantly, it was conceived that Melanotan II could be used to stimulate skin melanogenesis and development as a photoprotective or cosmetic drug. Additionally, Melanotan II and a similar α-MSH analogue, know as PT-141 or Bremelanotide, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

Quick Details

• Name: Melanotan-II
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
• Alias : Melanotan II, 7)-lactam, Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2;
• Ac-[Nle4,Asp5,D-Phe7,Lys10]alpha-MSH-(4-10)-NH2
• Molecular formula: C50H69N15O9
• MW : 1024.180
• CAS number: 121062-08-6
• MS:

• PubChem: 92432
• MeSH: melanotan-II
• Melanotan 2 Structural Name: Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10]α-MSH4-10-NH2
• Grade : Growth Hormone Peptides
• Purity : 98%
• Appearance : White Powder
• Package: 2mg/5mg/10mg/ vial;1g/bag
• Storage: Closed, below 2 ~ 8℃ preservation

• Delivery time : within 18 hours upon receipt of payment

• Delivery: EMS, DHL, TNT, FedEx, UPS

• Brand: NJBNSteroid

• Manufacturer : Nanjing Bangnuo Biotechnology Co., Ltd

• Skype: bnsteroid

• what's App: +8617327094661

• Email: annahuang@chembj.com

Functions & Traits

1. A Potential Treatment for Skin Cancer

• It is known that the effects of α-MSH are mediated by melanocortin receptors.

• MC1R is expressed in skin cells and has a high affinity for α-MSH and is the main receptor by which α-MSH signals.

• Based on this fundamental information, and observations of how α-MSH impacts melanomic cells, one study has hypothesized that "α-MSH acts initially to reduce initial tumor spread, but then paradoxically protects those cells that escape from the primary tumor.

• As an analog of α-MSH, it is logical to believe that Melanotan II may have similar effects.

     2. Treatment for Male and Female Sexual Dysfunction

• Melanotan-1, the precusor to Melanotan II, would eventually be licensed for commercialization as a tanning agent and has been in development for use as a potential "therapeutic tan," with minimal need for prolonged sun exposure. In the initial clinical testing of Melanotan II, an immediate and unexpected response was noted. The main subject experienced an erection shortly after administration. It was suggested that Melanotan II "may prove equally effective in women" as a "treatment of female sexual dysfunction. At least one study has observed that administration of Melanotan II may increase sexual desire, which should warrant further "investigation of centrally acting agents on disorders of sexual desire.
• Theoretically, Melanotan II may enhance sexual function in males (erectile activity) and females (increased levels of sexual desire and genital arousal). Unlike other sexual-enhancement drugs, it is hypothesizedd that Melanotan II works at a neurological level, eliciting a more "natural" sexual response with minimal side effects. It was suggested that Melanotan II "may prove equally effective in women" as a "treatment of female sexual dysfunction.[5] At least one study has observed that administration of Melanotan II may increase sexual desire, which should warrant further "investigation of centrally acting agents on disorders of sexual desire.

Specification

HPLC

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