Product Details:
Payment & Shipping Terms:
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Product Name: | Icariin | CAS: | 489-32-7 |
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MF: | C33H40O15 | MW: | 676.66 |
Mp: | 223-225 ºC | Density: | 1.55 |
Price: | Negotiated | Sample: | Free |
High Light: | steroid based hormones,natural steroid hormones |
Yellow Solid Sexual Human Growth Hormone Steroid CAS 489-32-7 Icariin
Basic Info:
Product name | Icariin |
Synonyms | Horny goat weed extract ; ICARIINE ; ICARRIN;epimedium extract ; Epimedium herb Ext ; Epimedium P.E ; Epimedium Brevicornum P.E ; Epimedim Brevicormum P.E |
CAS | 489-32-7 |
MF | C33H40O15 |
MW | 676.66 |
Chemical Properties | Light yellow to yellow solid |
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Usage | Male Sexual Enhancement |
Product Description:
COA:
Exterior
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Light yellow to yellow solid
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conform
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Degree of fineness
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100 mesh
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conform
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Loss on drying
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<5%
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3.5%
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Residue on ignition
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<2.5%
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2.1%
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Icariin
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>10%(HPLC)
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12.9%(HPLC)
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Distinguish
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(+)
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(+)
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Heavy Metal
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<5PPM
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conform
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bacterial
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<1000cfu/g
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40cfu/g
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Mold
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<100cfu/g
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<10cfu/g
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E. coli
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Negative
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Negative
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salmonella
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Negative
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Negative
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Storage conditions
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Top dry and low temperature sealing
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Top dry and low temperature sealing
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Conclusion
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conform
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Application:
To effectively treat bone diseases using bone regenerative medicine , there is an urgent need to develop safe cheap drugs that can potently induce bone formation . Here , we demonstrate the osteogenic effect of icariin , the main active compound of Epimedium pubescens . Icariin induced osteogenic differentiation in pre-osteoblastic MC3T3-E1 cells and mouse primary osteoblasts . Icariin upregulated the mRNA expression levels of the osteoblast marker genes runt-related transcription factor 2 (Runx2) and inhibitor of DNA-binding 1 (Id-1) . The osteogenic effect was inhibited by the introduction of Smad6 or dominant-negative Runx2 , as well as Noggin treatment . Furthermore , icariin induced the mRNA expression of bone morphogenetic protein (BMP)-4 . These data suggest that icariin exerts its potent osteogenic effect through induction of Runx2 expression , production of BMP-4 and activation of BMP signaling . The extremely low cost of icariin and its high abundance make it appealing for bone regenerative medicine .
Contact information:
seller | eve |
Skype | lxq1994yc |
eve@chembj.com | |
+8617327094392 | |
Feel free to contact! |