Hydrochloride Sex Steroid Hormones

Sex Steroid Hormones  Hydrochloride CAS 129938-20-1 For Male Sexual Function & Premature Ejaculation

• Sex Steroid Hormones Quick Detail:

Product name	Hydrochloride
CAS	129938-20-1
Content	98%min
MF	C9H7ClN2O5
MW	258.62
Character	White or off white powders
MP	175-177° C
MS.
Product Categories	Erectile Dysfunction , API , hydrochloride
Usage	HCl is a short-acting novel selective serotonin reuptake inhibitor, used for the treatment of premature ejaculation .
Skype	njbnsteroid
WhatsApp	+8617327093119
E-mail	gearmanager@chembj.com

• Sex Steroid Hormones Description:

1. hydrochloride is a drug that is used to treat premature ejaculation in men. It is available by prescription and is taken orally, prior to sexual intercourse. The drug belongs to the class called serotonin reuptake inhibitors (SSRIs), which have mainly been used to treat depression.
2. To treat premature ejaculation, both psychological and physiological factors need to be managed. From a pharmacological point-of-view, to treat the physiological aspect of premature ejaculation, hydrochloride is one of the first oral drugs to be made available. Psychological treatment may be given concomitantly, as the condition is multifactorial.
3. One of the possible adverse effects reported with SSRIs when used to treat depression is delayed ejaculation. This reported adverse effect led to the studies of hydrochloride, using the effect therapeutically. It is thought that serotonin may be involved in the inhibition of ejaculation. By blocking the serotonin reuptake in men suffering from premature ejaculation, the time to ejaculation may be prolonged.

• Sex Steroid Hormones Applications :

1. Treat male premature ejaculation and erectile dysfunction.
2. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE.
3. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction.
4. , on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug's accumulation in the body, and therefore reducing side effects.
5. Treat male premature ejaculation and erectile dysfunction. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger's meta analysis shows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when is used.

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