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Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal

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Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal

China Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal supplier
Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal supplier Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal supplier

Large Image :  Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal

Product Details:

Place of Origin: MADE IN CHINA
Brand Name: NJBN STEROID
Certification: ISO 9001; SGS; KOSHER
Model Number: 86386-73-4

Payment & Shipping Terms:

Minimum Order Quantity: 10 grame
Price: Negotiable
Packaging Details: 100g, 1kg/ foil bag; 10kg/25kg/drum
Payment Terms: Western Union, T/T, MoneyGram, Bitcoin
Supply Ability: 500kg/week
Detailed Product Description
Name: Fluconazole CAS: 86386-73-4
Appearance: White Powder Purity: 99% Min.
Price: Negotiable Delivery Time: Within One Working Day After Confirming The Payment
Function: Antifungal

 Factory Supply Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal

 

  • Quick Detail of Active Pharmaceutical Ingredients Fluconazole :

 

 

Product Name: Fluconazole

Synonyms:

FLUCONAZOLE;FLUCONAZOLE-D4;FLUCONAZOLE-D4 (BISMETHYLENE-D4);diflucan;2,4-DIFLUORO-ALPHA, ALPHA-1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;2,4-DIFLUORO-,1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;A-(2,4-DIFLUOROPHENYL)-A-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-1,2,4-TRIAZOL-1-ETHANOL;alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-triazole-1-ethanol;

 

CAS: 86386-73-4

EINECS: 200-659-6

MF: C13H12F2N6O;

MW: 306.27.

 

Product name: Fluconazole
Other Name: FLUCONAZOLE;FLUCONAZOLE-D4;FLUCONAZOLE-D4 (BISMETHYLENE-D4);diflucan;2,4-DIFLUORO-ALPHA, ALPHA-1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;2,4-DIFLUORO-,1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;A-(2,4-DIFLUOROPHENYL)-A-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-1,2,4-TRIAZOL-1-ETHANOL;alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-triazole-1-ethanol;
Original: China
CAS: 86386-73-4
EINECS: 200-659-6
Molecular formula: C13H12F2N6O
MW: 306.27
Brand name NJBNSteroid
Leading time within 24 hours upon receipt of payment
Delivery Fast and secure shipping by EMS, DHL, TNT, FedEx, UPS
Purity 99%
Package Discreet and Hidden package according to specific requirement
Appearance White powder
Certification SGS, ISO 9001, KOSHER
Payment Terms Western Union, Money Gram , T/T, Bitcoin
Minimum Order Quantity 10g
Price Negotiable
Usage For the treatment of fungal infections.
Molecular structure

 

Active Pharmaceuticals Ingredients Fluconazole CAS 86386-73-4 as an Antifungal

 

 

  • Description of Active Pharmaceutical Ingredients Fluconazole :

 

Fluconazole is a novel kind triazole drug of anti-fungal infection which was first successfully developed by the American Pfizer with broad-spectrum anti-fungal effect. It belongs to a kind of systemic anti-fungal products and has high selectivity on the inhibitory effect of the fungal cytochrome P450-dependent enzyme. It is also a kind of potent and specific inhibitor for the fungi alcohol synthesis.

 

Clinically it is mainly used for the treatment of vaginal candidiasis, thrush, atrophic oral candidiasis, fungal meningitis, pulmonary fungal infections, abdominal infections, urinary tract infections and skin fungi infection.

 

  • Main Indication for Active Pharmaceutical Ingredients Fluconazole :

 

(1) Systemic candidiasis: including candidemia, disseminated candidiasis and other forms of invasive Candida infections such as the peritoneum, endocardium, lungs and urinary tract infections. It can also be applied to patients of malignant tumors, special-care patients, patients who received radiotherapy, chemotherapy or immunosuppressive therapy as well as patients who are susceptible to other factors such as infection of Candida. It can also be used for prevention of the occurrence of candida infection for bone marrow transplant patients upon receiving cytotoxic drugs treatment or radiation treatment.

 

(2) Cryptococcosis: including cryptococcal meningitis and the cryptococcal infection in other parts (such as lung, skin). It can be applied to the patient of normal immune function, AIDS patients as well as patient of suppressed immune function due to organ transplant and other reasons. AIDS patients can administer this kind of drug for maintenance therapy and prevention of the relapse of cryptococcal disease.

 

(3) Mucosal candidiasis: including oropharyngeal, esophageal, non-invasive bronchial mucosal candidiasis, pulmonary candidiasis, Candida urine disease, mucocutaneous and chronic atrophic oral candidiasis. It can be applied to patients of both normal immune function and with impaired immune function.

 

(4) Fluconazole can be used as substitute of itraconazole for the treatment of blastomycosis and histoplasmosis.

 

(5) It can be used for the treatment of acute or recurrent vaginal candidiasis.

 

(6) For leukemia patients or patients of other malignant tumor who is susceptible to fungal infection upon undergoing chemotherapy or radiotherapy can apply it as means of preventive treatment.

It can be used for the treatment coccidioidomycosis.

 

(7) It can be used for treatment of fungal skin disease including fungal skin infections such as body ringworm, tinea pedis, tinea versicolor, tinea capitis, onychomycosis and nail ringworm.

 

(8) Fluconazole can also be used for the treatment of skin chromomycosis.

 

  • Medical Usage of Active Pharmaceutical Ingredients Fluconazole :

 

This product belongs to fluorinated triazole antifungal drug with the antifungal spectrum being similar as ketoconazole but antifungal activity being higher than ketoconazole. Its mechanism of action is through inhibition of essential component of the fungal cell membrane, the ergosterol biosynthesis enzyme, blocking the ergosterol synthesis and breaking the integrity of the fungal cell wall, further inhibiting their growth and reproduction.

 

The product has potent antifungal activity against Candida albicans, Microsporum canis, Cryptococcus neoformans, histoplasma capsulatum and epidermophyton.

 

  • Technical Testing Sheet of  Active Pharmaceutical Ingredients Fluconazole :

 

COA:

 


TEST ITEM

LIMT

TEST RESULTS

APPEARANCE

WHITE OR ALMOST WHITE,HYGROSCOPLE,CRYSTALLINE POWDER

CONFORMS

SOLUBILITY

SLIGHTLY SOLUBLE IN WATER,FREELY SOLUBLE IN METHANOL,SOLUBLE IN ACETONE

COMPLIES

IDENTIFICATION

TO COMPLY

COMPLIES

APPEARANCE OF SOLUTION

THE SOLUTION IS CLEAR AND COLORLESS

COMPLIES

RELATED SUBSTANCES %

IMPURITY A≤0.4
IMPURITY B≤0.3
IMPURITY C≤0.1
UNSPECIFIED IMPURITIES≤0.1
TOTAL IMPURITY≤0.6

0.3
NIL
NIL
0.02
0.32

HEAVY METALS %

≤0.001

<0.001

LOSS ON DRYING %

≤0.5

0.18

SULPHATED ASH %

≤0.1

<0.1

ASSAY (ON DRY BASIS) %

99.0-101.0

99.68

GRANULE SIZE

180 MICRON MAX

CONFORMS

CONCLUSION

CONFORMS TO EP5.6

 

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Delivery Time Usually 4-6 working days to reach destinations
Tracking number Offered once it is released on the Net .Normally within 24hours upon the receipt of payment.
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  • Please feel free to contact us when you are interested in the products above and the contact information are as following:

 

Contact Person: Jerry Zhang

E-mail: jerryzhang001@chembj.com

Skype: jerryzhang20161

WhatsApp: +8617327098732

 

Contact Details
Nanjing Bangnuo Biotechnology Co., Ltd

Contact Person: Jim

Tel: +8617327096639

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