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Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol

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Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol

China Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol supplier
Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol supplier Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol supplier Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol supplier Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol supplier

Large Image :  Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol

Product Details:

Place of Origin: MADE IN CHINA
Brand Name: NJBN
Certification: ISO9001 , SGS , KOSHER
Model Number: 163222-33-1

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Checking
Packaging Details: 1kg/25kgs
Delivery Time: 5~8 working days
Payment Terms: T/T, Western Union, MoneyGram, Bitcoin
Supply Ability: 1000kg per month
Detailed Product Description
Alias: Ezetimibe Purity: 99%
Appearance: White Powders Package: 1kg/25kg/piece
Dispatch Time: Within 24h After Payment Stock: Available
Samples: Free

High Purity Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol

 


Product Name: Ezetimibe
Synonyms: 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one;EZETIMIBE;ZETIA;Ezitimibe∬EzetimibeC24H21F2N03;(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, Sch-58235;1-(4-Flurophenyl)-(3R)-3-(4-flurophenyl)-(3S)-hydroxypropyl-(4S)-(4-hydroxyphenyl)-2-azetidinone;Ezetimide
CAS: 163222-33-1
MF: C24H21F2NO3
MW: 409.43
Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Final material;API;Isotope;CEDAX;Cardiovascular APIs;Ezetimibe
Melting point 164-166°C
Storage temp. -20℃ Freezer
Chemical Properties White Solid
Usage An antihyperlipoproteinemic. A Cholesterol absorption inhibitor
Usage antibacterial
Usage A cholesterol transport inhibitor that binds to NPC1L1
Usage For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia .

 

 

What is ezetimibe ?

 

Ezetimibe reduces the amount of cholesterol absorbed by the body.

Ezetimibe is used to treat high cholesterol.

Ezetimibe is sometimes given with other cholesterol-lowering medications.

 


Cholesterol-lowering drugs

 

Ezetimibe,jointly developed by Schering-Plough and Merck companies ,is the first selective cholesterol absorption inhibitor, the product is first approved by the US FDA listed as selective cholesterol absorption inhibitor class of drugs. Trade name is"EZETROL".

 

Ezetimibe is a new selective cholesterol absorption inhibitor, it is also the first selective inhibitor of intestinal cholesterol absorption, and its mechanism of action is different from other lipid-lowering agents (such as: statins, bile acid sequestrants, phenoxy acid derivative thereof cattle and plant sterol ester compound), the product ,through binding with the intestinal brush border membrane vesicle membrane protein (relative molecular mass 145X103), inhibits intestinal absorption of cholesterol which is from diet and transported to the intestine via the bile tract , reduces serum and liver cholesterol. Different from acid chelating agent ,ezetimibe does not affect cholesterol esters, other steroids (such as bezoar acid), triglycerides and fat-soluble vitamin absorption. Its pharmacological effects have nothing to do with acetyl coenzyme A- cholesterol acetyltransferase (ACAT) inhibiting and LDL receptors (scavenger receptor) expression . After being absorbed in the liver , ezetimibe combined with glucuronic acid by enterohepatic circulation,is almost specifically targeting to the small intestine mucosa. It can be used alone or in combination with HMG-CoA reductase inhibitors (statins) jointly applied to the treatment of primary (heterozygous familial and non-familial) hypercholesterolemia, homozygous familial hypercholesterolemia (HoFH) homozygous sitosterol hyperlipidemia (hyperlipidemia or phytosterols).

 

Ezetimibe is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin or Inegy) when statins alone do not control cholesterol.

 


Pharmaceutical Antihyperlipoproteinemic CAS 163222-33-1 Ezetimibe for High Cholesterol
 
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FAQ
 
Q1: Are you a manufacturer?
A: Yes, We manufacture bulk products in our factory located in Jiayu, Hubei, and produce small quantity and customer synthesis products in our lab located in Wuhan.
 
Q2: Do you have stock?
A: We understand most customers prefer stock, so we'll try to keep stock for most products. However, for some rare products, we won't keep stock and it needs time to synthesize.
 
Q3: What certificates and documents do you offer?
A: Some technical paperwork is available, such as COA, HNMR, HPLC, LC-MS etc.
 
Q4: Why should I choose you?
A: Powerful technical support-come from our highly skilled & fully experienced staff, working in chemical industry for over 5 years, in average.
Strict quality control-comes form our sophisticated management system.
Professional and warm sales team-since we believe we can only win via our hard work in a competitive world
Quick response and excellent presale and after sale service-since we believe our customers deserve all the best service
 
Q5: Can I get best price from you?
A: Of course. We don't chase excessive profits and always try tp give best offer. If you are good at bargaining, you can also enjoy fun of bargaining. Just don't make it too hard!
 
Q6: How should I pay?
A: We accept all kinds of payment ways. such as T/T, Western union, Moneygram , Bitcoin .
 
Q7: Do you provide free sample?
A: Yes, we can provide free sample if we have in stock, just need you to cover the delivery cost.
 
 

  • For more detailed information , pls feel free to contact me by the following ways :

 
Skype : njbnsteroid
WhatsApp : +8617327093119
E-mail : gearmanager@chembj.com
Website : www.realanabolicsteroids.com

Contact Details
Nanjing Bangnuo Biotechnology Co., Ltd

Contact Person: CPSS

Tel: +8617327093119

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