Payment & Shipping Terms:
|Assay:||99%||Usage:||Active Pharmaceutical Ingredients|
|Package:||1kg/aluminium Foil Bag Or As Required||Market:||Worldwide|
|Sample:||Free||Product Categories:||Active Pharmaceutical Ingredients|
High Quality 99.9% Active Pharmaceutical Ingredients Tianeptine sodium CAS 30123-17-2 With Good Price
Tianeptine Sodium--------Test Reports
|Product Name||Tianeptine sodium|
|Batch No:Mfg. date||Mfg. date: 2016-6-25|
|Test Date: 2016-6-25||Exp. date: 2018-6-24|
|Description||White to yellowish powder, very hygroscopic.||ff-white powder, very hygroscopic.|
|Solubility||Freetly soluble In water and methanol and dichloromethane||Complies|
1)By IR, To match with working standard.
(2)It gives reaction of sodium
|Impurities A||≤0.1%||Not detected|
Any impurity ≤0.1%
Total mpurities ≤0.4%
Acetone ≤ 0.5%
|Assay||99.0%-101.0%(On anhydrous basis)||99.98%|
|Conclusion||Conform to EP8.0|
Tianeptine is a drug used for treating major depressive episodes (mild, moderate, or severe). It has structural similarities to the tricyclic antidepressants, but it has different pharmacological properties. Tianeptine is a selective serotonin reuptake enhancer (SSRE), opposite to the action of SSRIs.
Tianeptine sodium,One review points to the cancellative effects of tianeptine and fluoxetine coadministration on serotonin reuptake. Another suggests that long-term administration of tianeptine has no effect on serotonin pathways. Tianeptine enhances the extracellular concentration of dopamine in the nucleus accumbens and modulates the D2 and D3 dopamine receptors. There is also action on the NMDA and AMPA receptors
Tianeptine Sodium--------Basic Information
|Product Name||Tianeptine sodium salt|
|Synonyms:||TIANEPTINE SODIUM;TIANEPTINE SODIUM SALT;sodium 7-((3-chloro-6,11-dihydro-6-methyldibenzo(c,f)(1,2)thiazepin-11-yl)amino)heptanoate s,s-dioxide;7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic Acid S,S-Dioxide Sodium Salt;S-1574;Stablon;7-[(3-chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid s,s dioxide sodium salt;Sodium 7-((3-chloro-6,11-dihydro-6-methyldibenzo(c,f)(1,2)thiazepin-11-yl)amino)heptanoate S,S-dioxide|
Tianeptine sodium is antidepressant. The animal has: the hippocampus pyramidal cells increased spontaneousactivity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampalneurons at sites of5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness;cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving.
Tianeptine sodium has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.
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