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Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8

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Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8

China Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8 supplier
Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8 supplier Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8 supplier Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8 supplier Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8 supplier

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Product Details:

Place of Origin: Mainland China
Brand Name: NJBNsteroid
Certification: SGS , ISO9001 , KOSHER
Model Number: 82640-04-8

Payment & Shipping Terms:

Minimum Order Quantity: 5g
Price: Negotiable
Packaging Details: 5g/10g/100g/1000g foil bag or as required
Delivery Time: Within One working day once against of the payment
Payment Terms: MoneyGram,Bitcion, , T/T, Western Union
Supply Ability: About 1000kg/per month
Detailed Product Description
Alias: Raloxifene HCL, KEOXIFENE CAS NO.: 82640-04-8
Category: Anti Estrogen Steroids Brand: NJBNSteroid
Appearance: Light Yellow Powder Purity: 99%
Melting Point: 250-253°C Application: Used In The Prevention Of Osteoporosis In Postmenopausal Women

 
Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8 ​
 
 
Raloxifene hydrochloride  description

Product nameRaloxifene hydrochloride
Other nameRaloxifene HCL;KEOXIFENE;AKOS 92138
Possible similar drugsEvista; Evista
CAS register number82640-04-8
Steroid ClassAnti Estrogen Steroids
AppearanceLight yellow powder
Molecular formulaC28H28ClNO4S
Molecular weight510.04
Molecular structureLight Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8
Melting point250-253°C
Assay99%
BrandNJBNsteroid
ManufacturerNanjing Bangnuo Biotechnology Co., Ltd
Treatment  forthe treatment/prevention of osteoporosis and reduction of breast cancer riskinpostmenopausalwomen.
StorageShading, confined preservation

 
Use in Cancer
 
Raloxifene hydrochloride is approved to prevent:

  • Breast cancer. It is used to decrease the chance of invasive breast cancer in postmenopausal women who have a high risk for developing the disease or who have osteoporosis.

Raloxifene hydrochloride is also approved to prevent and treat:

  • Osteoporosis in postmenopausal women.

Raloxifene hydrochloride is also being studied in the treatment of other types of cancer.
 
General Information
 
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism).
 
Evista is specifically approved for the treatment and prevention of osteoporosis in postmenopausal women, the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis and the reduction in risk of invasive breast cancer in postmenopausal women at high risk of invasive breast cancer. Evista is supplied as a 60 mg tablet designed for oral administration. The recommended initial dose of the drug is one 60 mg tablet daily, which may be administered any time of day without regard to meals.
 
Mechanism of Action
 
Evista (raloxifene hydrochloride) is an estrogen agonist/antagonist, referred to as a selective estrogen receptor modulator (SERM) and belongs to the benzothiophene class of compounds. The biological actions of raloxifene are largely mediated through binding to estrogen receptors. This binding results in activation of estrogenic pathways in some tissues (agonism) and and the blockade of estrogenic pathways in other tissues (antagonism). The agonistic or antagonistic activity of raloxiffene depends on the extent of recruitment of coactivators and corepressors to estrogen receptor (ER) target gene promotors. Raloxifene appears to act as an estrogen agonist in bone. It decreases bone resorption and bone turnover, increases bone mineral density and decreases fracture incidence.
 
Certificate of Analysis
 

ITEMSSPECIFICATIONRESULT
AppearanceWhite &off-white powderConforms
GradeAnti Estrogen SteroidsConforms

Solubility

Soluble in 10% sodium hydroxide solution. Slightly Soluble in methanol. Insoluble in water

Conforms

IdentificationsInfrared AbsorptionConforms

Loss on drying

≤0.5%0.4%
Residue on ignition≤0.1%0.06%
Heavy metals≤10ppmConforms

Raloxifene Impurity1

≤0.20 %0.10%
Any unspecified individual impurity 2

≤0.10%

Max. 0.08%
Total impurities≤0.50%0.40%
Raloxifene HCl≥98.0%99.0%

 
How to order quickly and safely ?
 

Step 1(Inquiry)Please let me know the items you are favorable, quantities, and the destination country.
Step 2 (Offer)We offer you price and the suitable shipping method for your reference.
Step 3 (Negotiation)We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service.
Step 4 (Order)After receiving your order, we will check it and get prepared for it.
Step 5 (Payment)Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.
Step 6 (Package & Delivery)Parcel will be arranged within 24 hours upon receipt of your payment . and photos will be offered to tell apart the products .
Step 7 (Tracking number)

If sent by EMS, the tracking number is availabe within 12 hours . The info will be trackable that day or next day.
If sent by HKEMS or other express,the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2 or 3 days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight.

Step 8 (After-Sales Service)Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results.

 
We are ready to serve you ,please contact without any doubt
 
Name:AnnaHuang
skype:bnsteroid
what'sApp:+8617327094661
Skype:bnsteroid
Email: annahuang@chembj.com

 
Light Yellow Powder Anti Estrogen Steroids Raloxifene Hydrochloride 82640-04-8

Contact Details
Nanjing Bangnuo Biotechnology Co., Ltd

Contact Person: CPSS

Tel: +8617327093119

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