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Procaine Hydrochloride Local Anesthetic Drugs

Procaine Hydrochloride Local Anesthetic Drugs

Large Image :  Procaine Hydrochloride Local Anesthetic Drugs

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MADE IN CHINA

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MADE IN CHINA

Detailed Product Description
CAS: 51-05-8 Port: HONGKONG
Appearance: Powder Color: White
Brand: NJBN STEROID Usage: Used To Infiltration, Spine And Conduction Anesthesia.
High Light:

regional anesthesia drugs

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local anesthesia medications

CAS 51-05-8 Local Anesthetic Drugs Procaine hydrochloride For Local Anesthesia

 

 

Local Anesthetic Drugs  Quick Detail:

 

Product Name Procaine HCl
Alias Procaine hydrochloride;aminocaine;anadolor;atoxicocaine
CAS NO 51-05-8
EINECS 200-077-2
Melting point 155-156 °C
Assay 99%
Storage Shading, confined preservation
Appearance White crystalline powder
Grade Pharmaceutical Grade
Brand NJBN STEROID
Delivery time Within 24 hours upon receipt of payment
Shipping EMS , DHL , TNT , FedEx , UPS
Usage Procaine hydrochloride is a kind of local anesthetics, for local anesthesia, nerve block etc, can block the conduction of nerve fibers with anesthetic effect, strong function, low toxicity, and no addiction, but the skin, mucous membrane penetration force is weak, not suitable for surface anesthesia, clinically used to infiltration, spine and conduction anesthesia.

 

Local Anesthetic Drugs  Specification:

 

COA:

 

Product name Procaine HCl
Appearance White crystalline powder
Assay (C13H20N2O2·HCl) 99.0% to 101.0% 99.5%
Melting point 153~158℃ 156.5~157.0℃
Heavy metals ≤20ppm <5ppm
Acidity ≤0.02N NaOH 0.5ml 0.3ml
Chromatographic purity Secondary spots≤0.5%,sum≤1.0% Conforms
Loss on drying ≤1.0% 0.06%
Residue on ignition ≤0.15% 0.03%
Bacterial endotoxins ≤0.6EU/mg <0.6EU/mg

 

HPLC:

 

Procaine Hydrochloride Local Anesthetic Drugs

 

Local Anesthetic Drugs  Product description:

 

  • PROCAINE HYDROCHLORIDE is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).
  • Procine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.
  • Procaine HCl (procaine hydrochloride) is the active ingredient in Gerovital H3(GH3) and in the Vitacels 3 through 8. Procaine HCl is broken down rapidly by enzymes in the blood stream into PABA and DEAE. The PABA and DEAE are rapidly conjugated and removed from the blood and excreted from the body. Because of this procaine HCl and its breakdown products (metabolites) are unable to get into the cells in any great quantity to produce benefits. Procaine HC will produce some benefits by itself, but they are very limited.

Local Anesthetic Drugs  Application:

 

  • Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
  • Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.
  • Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.other issues may occur because of varying individual tolerance to procaine dosage. nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.
  • Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

 

Order Guide

 

  • Q1: Have your Product Quality been Approved by Third Party Lab?

A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.

 

Procaine Hydrochloride Local Anesthetic Drugs
 

  • Q2: Is there any discount?

A: Yes, for larger quantity, we always support with better price.
 

  • Q3:How long does it take to the goods arrived ?

A:It is Depending on your location,For small order, please expect 5-7 days by DHL , UPS , TNT , FEDEX, EMS.for mass order, please allow 5-8 days by Air, 20-35 days by Sea.

 

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